It is important to specify your NEO Seed Nodes, if you want to get the NEO blockchain up and running on your machine. If you download the neo-gui from the NEO Project or neo-lux or neo-python from the City of Zion, you will run into issues synching the NEO blockchain....
Seed Nodes
A seed node is used to bootstrap the gossip process for new nodes joining a cluster. To learn the topology of the ring, a joining node contacts one of the nodes in the -seeds list in cassandra. yaml. The first time you bring up a node in a new cluster, only one node is the seed node.

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